SOLVER 4590 SOLVER MAXI WASH WASHABLE FLAT UTB

Chemwatch Material Safety Data Sheet

Issue Date: 19-Aug-2003

NC317TCP

CHEMWATCH 5089-91

Version No:3

Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

SOLVER 4590 SOLVER MAXI WASH WASHABLE FLAT UTB

SYNONYMS

"acrylic water based coating paint"

PRODUCT USE

Acrylic water based coating. Used according to manufacturer' s directions.

SUPPLIER

Company: Solver Paints Pty Ltd  Company: Solver Paints Pty Ltd
Address:                        Address:
211 Collier Rd                  560 Churchill Road
Bayswater                       Kilburn
WA, 6053                        SA, 5084
AUS                             AUS
Telephone: +61 8 9449 8811      Telephone: +61 8 8368 1200
Fax: +61 8 9371 5872            Emergency Tel: 1800 039 008 (24 hours)
                                Emergency Tel: +61 3 9573 3112
                                Fax: +61 8 8368 1222
                                

HAZARD RATINGS

Flammability 0
Toxicity 0
Body Contact 2
Reactivity 1
Chronic 2
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4

Section 2 - HAZARDS IDENTIFICATION

STATEMENT OF HAZARDOUS NATURE

NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of

NOHSC, and the ADG Code.

POISONS SCHEDULE

None

 

RISK SAFETY
Cumulative effects may result following exposure*. Do not breathe gas/fumes/vapour/spray.
May produce discomfort of the eyes*. Avoid contact with skin.
Limited evidence of a carcinogenic effect*. Wear eye/face protection.
* (limited evidence). In case of contact with eyes, rinse with plenty of water and contact Doctor or Poisons Information Centre.

Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS

NAME CAS RN %
acrylic polymer latex Not avail. 30-60
fillers including 2-20
calcium carbonate 471-34-1
filler, unregulated
titanium dioxide 13463-67-7 1-5
2, 2, 4- trimethyl- 1, 3- pentanediol monoisobutyrate 25265-77-4 1-<2
5- chloro- 2- methyl- 4- isothiazolin- 3- one 26172-55-4 <0.1
2- methyl- 4- isothiazolin- 3- one 2682-20-4 <0.1
additives 1-9
water 7732-18-5 10-30

Section 4 - FIRST AID MEASURES

SWALLOWED

· Immediately give a glass of water.

· First aid is not generally required. If in doubt, contact a Poisons Information Centre

or a doctor.

EYE

If this product comes in contact with the eyes:

· Wash out immediately with fresh running water.

· Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and

moving the eyelids by occasionally lifting the upper and lower lids.

· If pain persists or recurs seek medical attention.

· Removal of contact lenses after an eye injury should only be undertaken by skilled

personnel.

SKIN

If skin or hair contact occurs:

· Flush skin and hair with running water (and soap if available).

· Seek medical attention in event of irritation.

INHALED

· If fumes or combustion products are inhaled remove from contaminated area.

· Other measures are usually unnecessary.

NOTES TO PHYSICIAN

Treat symptomatically.

Section 5 - FIRE FIGHTING MEASURES

EXTINGUISHING MEDIA

· There is no restriction on the type of extinguisher which may be used.

· Use extinguishing media suitable for surrounding area.

FIRE FIGHTING

· Alert Fire Brigade and tell them location and nature of hazard.

· Wear breathing apparatus plus protective gloves for fire only.

· Prevent, by any means available, spillage from entering drains or water courses.

· Use fire fighting procedures suitable for surrounding area.

· DO NOT approach containers suspected to be hot.

· Cool fire exposed containers with water spray from a protected location.

· If safe to do so, remove containers from path of fire.

· Equipment should be thoroughly decontaminated after use.

FIRE/EXPLOSION HAZARD

· Non combustible.

· Not considered a significant fire risk, however containers may burn.

Decomposition may produce toxic fumes of:

carbon dioxide (CO2).

other pyrolysis products typical of burning organic material.

May emit poisonous fumes.

May emit corrosive fumes.

FIRE INCOMPATIBILITY

Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine

bleaches, pool chlorine etc. as ignition may result.

HAZCHEM: None

Section 6 - ACCIDENTAL RELEASE MEASURES

EMERGENCY PROCEDURES

MINOR SPILLS

Slippery when spilt.
·  Clean up all spills immediately.
·  Avoid breathing vapours and contact with skin and eyes.
·  Control personal contact by using protective equipment.
·  Contain and absorb spill with sand, earth, inert material or vermiculite.
·  Wipe up.
·  Place in a suitable labelled container for waste disposal.

MAJOR SPILLS

Slippery when spilt.
Moderate hazard.
· Clear area of personnel and move upwind.
· Alert Fire Brigade and tell them location and nature of hazard.
· Wear breathing apparatus plus protective gloves.
· Prevent, by any means available, spillage from entering drains or water course.
· Stop leak if safe to do so.
· Contain spill with sand, earth or vermiculite.
· Collect recoverable product into labelled containers for recycling.
· Neutralise/decontaminate residue.
· Collect solid residues and seal in labelled drums for disposal.
· Wash area and prevent runoff into drains.
· After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
· If contamination of drains or waterways occurs, advise emergency services.

EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)

The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
    for up to one hour WITHOUT experiencing or developing

  life-threatening health effects is:
    water  500 mg/m³

  irreversible or other serious effects or symptoms which could impair an individual's ability to take
    protective action is:
    water  500 mg/m³

  other than mild, transient adverse effects without perceiving a clearly defined odour is:
    water  500 mg/m³

  The threshold concentration below which most people will experience no appreciable risk of health effects:
    water  500 mg/m³

American Industrial Hygiene Association (AIHA)

Ingredients considered according to the following cutoffs
  Very Toxic (T+)  >= 0.1%          Toxic (T)       >= 3.0%
  R50              >= 0.25%         Corrosive (C)   >= 5.0%
  R51              >= 2.5%
else               >= 10%
where percentage is percentage of ingredient found in the mixture

SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS

___________________________________________

+ + + + + +

___________________________________________

+:  May be stored together
O:  May be stored together with specific preventions
X:  Must not be stored together

 

 

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

Section 7 - HANDLING AND STORAGE

PROCEDURE FOR HANDLING

· Avoid all personal contact, including inhalation.

· Wear protective clothing when risk of exposure occurs.

· Use in a well-ventilated area.

· Avoid contact with moisture.

· Avoid contact with incompatible materials.

· When handling, DO NOT eat, drink or smoke.

· Keep containers securely sealed when not in use.

· Avoid physical damage to containers.

· Always wash hands with soap and water after handling.

· Work clothes should be laundered separately. Launder contaminated clothing before re

-use.

· Use good occupational work practice.

· Observe manufacturer's storing and handling recommendations.

· Atmosphere should be regularly checked against established exposure standards to ensure

safe working conditions are maintained.

SUITABLE CONTAINER

· Polyethylene or polypropylene container.

· Packing as recommended by manufacturer.

· Check all containers are clearly labelled and free from leaks.

STORAGE INCOMPATIBILITY

Avoid reaction with oxidising agents.

STORAGE REQUIREMENTS

· Store in original containers.

· Keep containers securely sealed.

· Store in a cool, dry, well-ventilated area.

· Store away from incompatible materials and foodstuff containers.

· Protect containers against physical damage and check regularly for leaks.

· Observe manufacturer's storing and handling recommendations.

Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION

EXPOSURE CONTROLS

Source              Material            TWA     TWA     STEL    STEL    Peak     Peak     TWA
                                        ppm     mg/m³   ppm     mg/m³   ppm      mg/m³    F/CC
_________________   __________________  _____   _____   _____   _____   _____    _____    _____

 

Source              Material            TWA     TWA     STEL    STEL    Peak     Peak     TWA
                                        ppm     mg/m³   ppm     mg/m³   ppm      mg/m³    F/CC
_________________   __________________  _____   _____   _____   _____   _____    _____    _____
Australia Exposure  calcium carbonate           10
Standards           (Calcium carbonate
                    (a))
Australia Exposure  titanium dioxide            10
Standards           (Titanium dioxide
                    (a))

The following materials had no OELs on our records
  • 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate:      CAS:25265-77-4     CAS:77-68-9
  • 5-chloro-2-methyl-4-isothiazolin-3-one:      CAS:26172-55-4
  • 2-methyl-4-isothiazolin-3-one:      CAS:2682-20-4
  • water:      CAS:7732-18-5

 

EMERGENCY EXPOSURE LIMITS

Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
titanium dioxide 5,000

 

MATERIAL DATA

Not available. Refer to individual constituents.

INGREDIENT DATA

2,2,4-TRIMETHYL-1,3-PENTANEDIOL MONOISOBUTYRATE:
ACRYLIC POLYMER LATEX:
WATER:
   No exposure limits set by NOHSC or ACGIH.

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
TITANIUM DIOXIDE:
   Sensory irritants are chemicals that produce temporary and undesirable side-effects on
the eyes, nose or throat. Historically occupational exposure standards for these
irritants have been based on observation of workers' responses to various airborne
concentrations. Present day expectations require that nearly every individual should be
protected against even minor sensory irritation and exposure standards are established
using uncertainty factors or safety factors of 5 to 10 or more. On occasion animal no
-observable-effect-levels (NOEL) are used to determine these limits where human results
are unavailable. An additional approach, typically used by the TLV committee (USA) in
determining respiratory standards for this group of chemicals, has been to assign ceiling
values (TLV C) to rapidly acting irritants and to assign short-term exposure limits (TLV
STELs) when the weight of evidence from irritation, bioaccumulation and other endpoints
combine to warrant such a limit. In contrast the MAK Commission (Germany) uses a five
-category system based on intensive odour, local irritation, and elimination half-life.
However this system is being replaced to be consistent with the European Union (EU)
Scientific Committee for Occupational Exposure Limits (SCOEL); this is more closely
allied to that of the USA.
   OSHA (USA) concluded that exposure to sensory irritants can:
   · cause inflammation
   · cause increased susceptibility to other irritants and infectious agents
   · lead to permanent injury or dysfunction
   · permit greater absorption of hazardous substances and
   · acclimate the worker to the irritant warning properties of these substances thus
increasing the risk of overexposure.

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   CEL TWA: 0.1 mg/m3; STEL 0.3 mg/m3 total isothiazolinones (Rohm and Haas).

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   MAK values, and categories and groups are those recommended within the
   Federal Republic of Germany.

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   MAK Group D: Classification as to the effect of the substance on the developing
embryo/foetus is not yet possible because although data may indicate a trend, they are
not sufficient for a final evaluation.

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   Designated S in List of MAK values: Danger of sensitization.

CALCIUM CARBONATE:
   The TLV-TWA is thought to be protective against the significant risk of
   physical irritation associated with exposure.

TITANIUM DIOXIDE:
   It is the goal of the ACGIH (and other Agencies) to recommend TLVs (or their
equivalent) for all substances for which there is evidence of health effects at airborne
concentrations encountered in the workplace.
   At this time no TLV has been established, even though this material may produce
adverse health effects (as evidenced in animal experiments or clinical experience).
Airborne concentrations must be maintained as low as is practically possible and
occupational exposure must be kept to a minimum.
   NOTE: The ACGIH occupational exposure standard for Particles Not Otherwise Specified
(P.N.O.S) does NOT apply.
   WARNING: This substance has been classified by the IARC as Group 2B: Possibly
Carcinogenic to Humans.
   IDLH Level: 5000 mg/m3
   Animal studies at 10 mg/m3 show no significant fibrosis, possibly reversible
   tissue reaction and the architecture of lung air spaces remains intact.

5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   MAK values, and categories and groups are those recommended within the
   Federal Republic of Germany.
   CEL TWA: 0.1 mg/m3; STEL: 0.3 mg/m3  total isothiazolines  [Manufacturer]
   MAK value: 0.2 mg/m3

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
   MAK values, and categories and groups are those recommended within the
   Federal Republic of Germany.
   MAK value: 0.05 mg/m3

PERSONAL PROTECTION

EYE

· Safety glasses with side shields.
· Chemical goggles.
· Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].

HANDS/FEET

Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.

OTHER

· Overalls.
· P.V.C. apron.
· Barrier cream.
· Skin cleansing cream.
· Eye wash unit.

RESPIRATOR

Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.

Breathing Zone Level ppm (volume) Maximum Protection Factor Half-face Respirator Full-Face Respirator
1000 10 AK-AUS P -
1000 50 - AK-AUS P
5000 50 Airline * -
5000 100 - AK-2 P
10000 100 - AK-3 P
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand. The local concentration of material, quantity and conditions of use determine the type of personal protective equipment required. For further information consult site specific CHEMWATCH data (if available), or your Occupational Health and Safety Advisor.

ENGINEERING CONTROLS

General exhaust is adequate under normal operating conditions. Local exhaust ventilation
may be required in specific circumstances. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Provide adequate
ventilation in warehouse or closed storage areas. Air contaminants generated in the
workplace possess varying "escape" velocities which, in turn, determine the "capture
velocities" of fresh circulating air required to effectively remove the contaminant.

Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating from tank (in still air). 0.25-0.5 m/s (50-100 f/min)
aerosols, fumes from pouring operations, intermittent container filling, low speed conveyer transfers, welding, spray drift, plating acid fumes, pickling (released at low velocity into zone of active generation) 0.5-1 m/s (100-200 f/min.)
direct spray, spray painting in shallow booths, drum filling, conveyer loading, crusher dusts, gas discharge (active generation into zone of rapid air motion) 1-2.5 m/s (200-500 f/min.)
grinding, abrasive blasting, tumbling, high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). 2.5-10 m/s (500-2000 f/min.)
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to capture 1: Disturbing room air currents
2: Contaminants of low toxicity or of nuisance value only. 2: Contaminants of high toxicity
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood-local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example, should be a minimum of 1-2 m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from the extraction point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE

White liquid with a characteristic odour; mixes with water.

PHYSICAL PROPERTIES

Liquid.

Mixes with water.

 

Molecular Weight: Not Available Boiling Range (�C): 100
Melting Range (�C): Not Available Specific Gravity (water=1): 1.09-1.16
Solubility in water (g/L): Miscible pH (as supplied): 9.0-9.5
pH (1% solution): Not Available Vapour Pressure (kPa): Not Available
Volatile Component (%vol): Not Available Evaporation Rate: Not Available
Relative Vapour Density (air=1): Not Available Flash Point (�C): Not Available
Lower Explosive Limit (%): Not Available Upper Explosive Limit (%): Not Available
Autoignition Temp (�C): Not Available Decomposition Temp (�C): Not Available
State: Liquid Viscosity: Not available

Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION

CONDITIONS CONTRIBUTING TO INSTABILITY

· Presence of incompatible materials.

· Product is considered stable.

· Hazardous polymerisation will not occur.

Section 11 - TOXICOLOGICAL INFORMATION

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

The material has NOT been classified by EC Directives or other classification systems as
"harmful by ingestion". This is because of the lack of corroborating animal or human
evidence. The material may still be damaging to the health of the individual, following
ingestion, especially where pre-existing organ (eg. liver, kidney) damage is evident.
Present definitions of harmful or toxic substances are generally based on doses producing
mortality rather than those producing morbidity (disease, ill-health). Gastrointestinal
tract discomfort may produce nausea and vomiting. In an occupational setting however,
ingestion of insignificant quantities is not thought to be cause for concern.

EYE

There is some evidence to suggest that this material can cause eye irritation and damage
in some persons.

SKIN

The material is not thought to produce adverse health effects or skin irritation
following contact (as classified by EC Directives using animal models). Nevertheless,
good hygiene practice requires that exposure be kept to a minimum and that suitable
gloves be used in an occupational setting.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may
produce systemic injury with harmful effects. Examine the skin prior to the use of the
material and ensure that any external damage is suitably protected.

INHALED

The material is not thought to produce adverse health effects or irritation of the
respiratory tract (as classified by EC Directives using animal models). Nevertheless,
good hygiene practice requires that exposure be kept to a minimum and that suitable
control measures be used in an occupational setting.

CHRONIC HEALTH EFFECTS

Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure.
There has been some concern that this material can cause cancer or mutations but there is
not enough data to make an assessment.
Long term exposure to titanium and several of its compounds produces lung scarring and
chronic bronchitis. Breathing is impaired and cardiac changes with right heart
enlargements occur. There is an increased chance of developing cancers of the respiratory
tract.

TOXICITY AND IRRITATION

None assigned. Refer to individual constituents.

ACRYLIC POLYMER LATEX:
TOXICITY                                  IRRITATION
Oral (rat) LD50: >5000 mg/kg      [Manfr.RH]
Acrylic polymer emulsions may contain residual traces of odourous acrylic monomers; the
amounts remaining in compounded mixtures represents a very low order of exposure, however
this may become noticeable with some materials particularly in confined or poorly
ventilated spaces.

CALCIUM CARBONATE:
TOXICITY                                            IRRITATION
Oral (rat) LD50: 6450 mg/kg                         Skin (rabbit): 500 mg/24h- Moderate
Eye (rabbit): 0.75 mg/24h - SEVERE
No evidence of carcinogenic properties.  No evidence of mutagenic or
teratogenic effects.

TITANIUM DIOXIDE:
TOXICITY                                            IRRITATION
Skin (human): 0.3 mg/3d- I Mild
The material may produce moderate eye irritation leading to inflammation. Repeated or
prolonged exposure to irritants may produce conjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.

2,2,4-TRIMETHYL-1,3-PENTANEDIOL MONOISOBUTYRATE:
TOXICITY                                            IRRITATION
Oral (rat) LD50: 3200 mg/kg                         Skin - Slight Irritant *
Oral (rat) LD50: 3200 mg/kg ***                     Skin (rabbit): Mild ***
Dermal (rabbit) LD50: > 16 ml/kg *                  Eyes - Moderate Irritant *
Dermal (g.pig) LD50: >16 ml/kg ***
Inhalation (rat) LC50: >3.55 mg/l/6h
Inhalation (rat) LC50: 1600 mg/kg ***               Eye (rabbit): Mild ***
Skin sensitisation (guinea pig): none. *
Not a skin sensitiser (guinea pig, Magnusson-Kligman) ***
Ames Test: negative ***
Micronucleus, mouse: negative ***
Not mutagenic ***
No effects on fertility or foetal development seen in the rat ***
*  [SWIFT]
** [Eastman]
*** [Perstop]

5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria
or Quincke's oedema. The pathogenesis of contact eczema involves a cell-mediated (T
lymphocytes) immune reaction of the delayed type. Other allergic skin reactions, e.g.
contact urticaria, involve antibody-mediated immune reactions. The significance of the
contact allergen is not simply determined by its sensitisation potential: the
distribution of the substance and the opportunities for contact with it are equally
important. A weakly sensitising substance which is widely distributed can be a more
important allergen than one with stronger sensitising potential with which few
individuals come into contact. From a clinical point of view, substances are noteworthy
if they produce an allergic test reaction in more than 1% of the persons tested.
The material may be irritating to the eye, with prolonged contact causing inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
Asthma-like symptoms may continue for months or even years after exposure to the material
ceases. This may be due to a non-allergenic condition known as reactive airways
dysfunction syndrome (RADS) which can occur following exposure to high levels of highly
irritating compound. Key criteria for the diagnosis of RADS include the absence of
preceding respiratory disease, in a non-atopic individual, with abrupt onset of
persistent asthma-like symptoms within minutes to hours of a documented exposure to the
irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to
severe bronchial hyperreactivity on methacholine challenge testing and the lack of
minimal lymphocytic inflammation, without eosinophilia, have also been included in the
criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of exposure
to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that
occurs as result of exposure due to high concentrations of irritating substance (often
particulate in nature) and is completely reversible after exposure ceases. The disorder
is characterised by dyspnea, cough and mucus production.
NOTE: Substance has been shown to be mutagenic in at least one assay, or belongs to a
family of chemicals producing damage or change to cellular DNA.
No significant acute toxicological data identified in literature search.
Considered to be the major sensitiser in Kathon CG (1)
(1). Bruze etal - Contact Dermatitis 20: 219-39, 1989

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria
or Quincke's oedema. The pathogenesis of contact eczema involves a cell-mediated (T
lymphocytes) immune reaction of the delayed type. Other allergic skin reactions, e.g.
contact urticaria, involve antibody-mediated immune reactions. The significance of the
contact allergen is not simply determined by its sensitisation potential: the
distribution of the substance and the opportunities for contact with it are equally
important. A weakly sensitising substance which is widely distributed can be a more
important allergen than one with stronger sensitising potential with which few
individuals come into contact. From a clinical point of view, substances are noteworthy
if they produce an allergic test reaction in more than 1% of the persons tested.
The material may be irritating to the eye, with prolonged contact causing inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
Asthma-like symptoms may continue for months or even years after exposure to the material
ceases. This may be due to a non-allergenic condition known as reactive airways
dysfunction syndrome (RADS) which can occur following exposure to high levels of highly
irritating compound. Key criteria for the diagnosis of RADS include the absence of
preceding respiratory disease, in a non-atopic individual, with abrupt onset of
persistent asthma-like symptoms within minutes to hours of a documented exposure to the
irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to
severe bronchial hyperreactivity on methacholine challenge testing and the lack of
minimal lymphocytic inflammation, without eosinophilia, have also been included in the
criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of exposure
to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that
occurs as result of exposure due to high concentrations of irritating substance (often
particulate in nature) and is completely reversible after exposure ceases. The disorder
is characterised by dyspnea, cough and mucus production.
No significant acute toxicological data identified in literature search.
NOTE: Substance has been shown to be mutagenic in at least one assay, or belongs to a
family of chemicals producing damage or change to cellular DNA.
Considered to be a minor sensitiser in Kathon CG (1)
(1). Bruze etal - Contact Dermatitis 20: 219-39, 1989

WATER:
No significant acute toxicological data identified in literature search.

 

MATERIAL                  CARCINOGEN            REPROTOXIN        SENSITISER        SKIN
________________________  ____________________  ________________  ________________  ________________
titanium dioxide          IARC:2B

CARCINOGEN
   IARC: International Agency for Research on Cancer (IARC) Carcinogens: titanium dioxide
    Category: 2B

Section 12 - ECOLOGICAL INFORMATION

DO NOT discharge into sewer or waterways.
Refer to data for ingredients, which follows:

TITANIUM DIOXIDE:
DO NOT discharge into sewer or waterways.

2,2,4-TRIMETHYL-1,3-PENTANEDIOL MONOISOBUTYRATE:
log Kow 3.54
Potential for bioaccumulation but not considered as significant due to
ready biodegradability.
Degradation
BOD28/ ThOD 88.7%  (Test method) OECD 301 C
Readily biodegradable
Atmospheric residence time: T(OH)=403 hrs.
Ecotoxicology:
Aquatic toxicity:
Fish LC50 (96 h): fathead minnow, 33 mg/l, NOEC: 16mg/l
sideswimmer, >95 mg/l (highest concentration tested)
Fish LC50 (96 h): oncorhynchus mykiss, >19 mg/l *
Daphnia magna EC50, (48 h): >19 mg/l *
Chaetgammarus marinus EC50 (96 h): 40 mg/l (seawater, 15 C.) *
Algae EC50 (72 h): 15 mg/l *
Daphnia EC50 (48h): 147.8 mg/l, NOEC: 28.4 mg/l
Pill bug LC50 (96h): >95 mg/l (highest concentration tested)
Flatworm LC50 (96h): 38 mg/l, NOEC: 9.5 mg/l
Aquatic earthworm LC50 (96 h): 30.4 mg/l, NOEC: 9.5 mg/l
Ramshorn snail LC50 (96h): >95 mg/l (highest concentration tested)
Selenastrum capricornutum EC50 (72 h): 18.4 mg/l
COD: 2.2 g/g
BOD: 2.4 g/g                                                    Eastman
* Perstop
WGK=1 (weakly water endangering)
WGK: Classification in accordance with German Water Resources Act.

5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE:
The isothiazolinones are very toxic to marine organisms (fish, Daphnia magna and algae)
The high water solubility and low log Kow values of several chlorinated and non
-chlorinated indicate a low potential for bioaccumulation.
Studies of 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) in bluegill sunfish (Lepornis
machrochirus) show BCF values of 102, 114 and 67 at nominal concentrations of 0.02, 0.12
and 0.8 mg/l. The BCF for 2-methyl-4-isothiazolin-3-one (MI) was determined at 2.3 at a
nominal concentration of 0.12 mg/l
Primary biodegradation of MI and CMI occurred with half-lives of less than 24 hours in
aerobic and anoxic sediments, and within a period of less than one week the parent
compounds were depleted to very low levels that could not be clearly distinguished from
analytical artifacts. The ultimate aerobic biodegradability of both MI and CMI attained
levels of > 55% within 29 days. Furthermore, the proposed metabolites of MI and CMI are
considered to have a low aquatic toxicity on the basis of QSAR estimates and the measured
toxicity of the structurally related N-(n-octyl) malonamic acid.
Prevent, by any means available, spillage from entering drains or water
courses.
Do NOT allow product to come in contact with surface waters or to intertidal areas below
the mean high water mark. Do not contaminate water when cleaning equipment or disposing
of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste
sites.
DO NOT discharge into sewer or waterways.
Octanol/water Coefficient = 0.401 (log P)
Biodegradation (aquatic metabolism)
half life t1/2 anerobic = 4.8 hours
half life t1/2 aerobic = 17.3 hours
as mixed isothiazolinones
Rainbow trout  LC50(96 hr) = 0.19 mg/L.
Bluegill Sunfish LC50(96hr) = 0.28 mg/L.
Daphnia EC50(48hr) = 0.16 mg/L.
Algal Selenastrum EC50: 0.018 mg/L.

2-METHYL-4-ISOTHIAZOLIN-3-ONE:
The isothiazolinones are very toxic to marine organisms (fish, Daphnia magna and algae)
The high water solubility and low log Kow values of several chlorinated and non
-chlorinated indicate a low potential for bioaccumulation.
Studies of 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) in bluegill sunfish (Lepornis
machrochirus) show BCF values of 102, 114 and 67 at nominal concentrations of 0.02, 0.12
and 0.8 mg/l. The BCF for 2-methyl-4-isothiazolin-3-one (MI) was determined at 2.3 at a
nominal concentration of 0.12 mg/l
Primary biodegradation of MI and CMI occurred with half-lives of less than 24 hours in
aerobic and anoxic sediments, and within a period of less than one week the parent
compounds were depleted to very low levels that could not be clearly distinguished from
analytical artifacts. The ultimate aerobic biodegradability of both MI and CMI attained
levels of > 55% within 29 days. Furthermore, the proposed metabolites of MI and CMI are
considered to have a low aquatic toxicity on the basis of QSAR estimates and the measured
toxicity of the structurally related N-(n-octyl) malonamic acid.
Prevent, by any means available, spillage from entering drains or water
courses.
Do NOT allow product to come in contact with surface waters or to intertidal areas below
the mean high water mark. Do not contaminate water when cleaning equipment or disposing
of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste
sites.
DO NOT discharge into sewer or waterways.
The material is classified as an ecotoxin* because the Fish LC50 (96 hours) is less than
or equal to 0.1 mg/l

* Classification of Substances as Ecotoxic (Dangerous to the Environment)
  Appendix 8, Table 1
Compiler's Guide for the Preparation of International Chemical Safety Cards: 1993
Commission of the European Communities.
Octanol/ water coefficient = -0.486 (log P)
Biodegradation (aquatic metabolism)
half life t1/2 (aerobic) =9.1 hours
as mixed isothiazolinones
Rainbow trout LC50(96hr): = 0.19 mg/L.
Bluegill sunfish LC50(96hr): = 0.28 ml/L.
Daphnia EC50(48hr): = 0.16 mg/L.
Algal (Selenastrum) EC50: 0.018 mg/L.

Section 13 - DISPOSAL CONSIDERATIONS

· Recycle wherever possible.

· Consult manufacturer for recycling options or consult local or regional waste

management authority for disposal if no suitable treatment or disposal facility can be

identified.

· Dispose of by: Burial in a licenced land-fill or incineration in a licenced apparatus

(after admixture with suitable combustible material).

· Decontaminate empty containers. Observe all label safeguards until containers are

cleaned and destroyed.

· Containers may still present a chemical hazard/ danger when empty.

· Return to supplier for reuse/ recycling if possible.

Otherwise:

· If container can not be cleaned sufficiently well to ensure that residuals do not

remain or if the container cannot be used to store the same product, then puncture

containers, to prevent re-use, and bury at an authorised landfill.

· Where possible retain label warnings and MSDS and observe all notices pertaining to the

product.

Section 14 - TRANSPORTATION INFORMATION

Labels Required: 
HAZCHEM: None


NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG

Section 15 - REGULATORY INFORMATION

POISONS SCHEDULE: None

REGULATIONS

acrylic polymer latex (CAS No:Not avail):
No regulations applicable

calcium carbonate (CAS: 471-34-1) is found on the following regulatory lists;
 Australia - Australia New Zealand Food Standards Code - Food Additives - Schedule 1
Permitted uses of food additives by food type
 Australia High Volume Industrial Chemical List (HVICL)
 Australia Inventory of Chemical Substances (AICS)
 CODEX General Standard for Food Additives (GSFA) - Additives Permitted for Use in Food
in General, Unless Otherwise Specified, in Accordance with GMP
 International Council of Chemical Associations (ICCA) - High Production Volume List
 OECD Representative List of High Production Volume (HPV) Chemicals
calcium carbonate (CAS: 1317-65-3) is found on the following regulatory lists;
 Australia - Australia New Zealand Food Standards Code - Food Additives - Schedule 1
Permitted uses of food additives by food type
 Australia Exposure Standards
 Australia Inventory of Chemical Substances (AICS)
 OECD Representative List of High Production Volume (HPV) Chemicals

titanium dioxide (CAS: 13463-67-7) is found on the following regulatory lists;
 Australia - Australia New Zealand Food Standards Code - Food Additives - Schedule 3
Colours permitted in accordance with GMP in processed foods specified in Schedule 1
 Australia Exposure Standards
 Australia High Volume Industrial Chemical List (HVICL)
 Australia Inventory of Chemical Substances (AICS)
 Australia Therapeutic Goods Administration (TGA) Sunscreening agents permitted as active
ingredients in listed products
 CODEX General Standard for Food Additives (GSFA) - Additives Permitted for Use in Food
in General, Unless Otherwise Specified, in Accordance with GMP
 International Agency for Research on Cancer (IARC) Carcinogens
 OECD Representative List of High Production Volume (HPV) Chemicals

2,2,4-trimethyl-1,3-pentanediol monoisobutyrate (CAS: 25265-77-4) is found on the
following regulatory lists;
 Australia High Volume Industrial Chemical List (HVICL)
 Australia Inventory of Chemical Substances (AICS)
 IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid Substances Carried in Bulk
 OECD Representative List of High Production Volume (HPV) Chemicals
2,2,4-trimethyl-1,3-pentanediol monoisobutyrate (CAS: 77-68-9) is found on the following
regulatory lists;
 Australia Inventory of Chemical Substances (AICS)

5-chloro-2-methyl-4-isothiazolin-3-one (CAS: 26172-55-4) is found on the following
regulatory lists;
 Australia Inventory of Chemical Substances (AICS)
 OECD Representative List of High Production Volume (HPV) Chemicals

2-methyl-4-isothiazolin-3-one (CAS: 2682-20-4) is found on the following regulatory lists
;
 Australia Inventory of Chemical Substances (AICS)

water (CAS: 7732-18-5) is found on the following regulatory lists;
 Australia Inventory of Chemical Substances (AICS)
 OECD Representative List of High Production Volume (HPV) Chemicals

No data available for acrylic polymer latex as CAS: Not avail.
No data available for calcium carbonate as CAS: 13397-26-7, CAS: 15634-14-7.

Section 16 - OTHER INFORMATION

Denmark Advisory list for selfclassification of dangerous substances

Substance                                 CAS         Suggested codes
5- chloro- 2- methyl- 4- isothiazolin-    26172- 55-  R43
3- one                                    4
2- methyl- 4- isothiazolin- 3- one        2682- 20-   R43
                                          4

 

INGREDIENTS WITH MULTIPLE CAS NUMBERS

Ingredient Name CAS
calcium carbonate 471-34-1, 13397-26-7, 15634-14-7, 1317-65-3
2,2,4-trimethyl-1,3-pentanediol monoisobutyrate 25265-77-4, 77-68-9

EXPOSURE STANDARD FOR MIXTURES

"Worst Case" computer-aided prediction of spray/ mist or fume/ dust components and
concentration:
 
Composite Exposure Standard for Mixture (TWA) :0.1 mg/m³.
Operations which produce a spray/mist or fume/dust, introduce particulates to the
breathing zone.
If the breathing zone concentration of ANY of the components listed below is exceeded,
"Worst Case" considerations deem the individual to be overexposed.
Component   Breathing Zone ppm    Breathing Zone mg/m3   Mixture Conc (%).

Component                           Breathing Zone  Mixture Conc
                                    (mg/m³)         (%)
5-chloro-2-methyl-4-isothiazolin-3  0.1000          0.1

 

This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or

criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission

from CHEMWATCH. TEL (+61 3) 9572 4700.

 

Issue Date: 19-Aug-2003

Print Date: 16-Mar-2007